Oxytocin Receptors in Guinea Pig Myometrium Near Term and During Labor1
نویسندگان
چکیده
منابع مشابه
Desensitization of oxytocin receptors in human myometrium.
In the present study, we investigated the possible mechanisms by which oxytocin might regulate oxytocin receptor (OTR) density. Exposure of cultured myometrial cells to oxytocin for a prolonged period caused desensitization: the steady-state level of oxytocin binding was 210 x 10(3) binding sites/cell, but this was time-dependently reduced to 20.1 x 10(3) sites/cell by exposing the cells to oxy...
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The objective of the present study was to further elucidate our previous observation that beta2-adrenoceptor activation induces oxytocin receptor (OTR) expression in rat myometrium. We wanted to investigate whether the mechanism behind this effect was under the influence of gonadal steroids. Ovariectomized non-pregnant rats were treated with estrogen, progesterone or a combination of both for 3...
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ژورنال
عنوان ژورنال: Biology of Reproduction
سال: 2000
ISSN: 0006-3363,1529-7268
DOI: 10.1095/biolreprod62.2.427